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apalutamide will minimize the extent or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with drugs that are CYP3A4 substrates may result in reduce publicity to those medications.A healthcare Expert need to be consulted in adv